Preclinical Testing

Sample Collection & Preparation

Let's ensure your important samples reach our laboratory safely.

Below, please find information about sample collection, storage and shipping for our portfolio preclinical tests.

For additional shipping information, please visit our shipping page.

To request preclinical testing supplies, please visit our supply order page.

Hematology sample collection & shipping

Comprehensive information on procedures for sample collection, detailed instructions on the packaging and shipping process, and additional details for hematology.

Sample Requirements - Icon

Sample Requirements

EDTA whole blood in a lavendar top tube (LTT) is the preferred sample for most hematology services.

Heparin-anticoagulated whole blood in a green top tube (GNTT) or sodium citrated whole blood in a blue top tube (BTT) are also acceptable

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Collection Instructions

Standard CBCs require 150 µL.

Dilution strategies are also available for lower volumes.

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Sample Storage

Refrigerate samples at 2-8°C, samples cannot be frozen.

Samples should be analyzed within 72 hours for optimal results.

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Shipping

Ship on the same day as collection.

Keep refrigerated on cold packs and prevent from freezing.

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Turnaround Time

Most standard assays are reported within 1-3 business days.

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Additional Information

Dilution strategies are possible. Please consult with your account manager.

Please refer to our Tube Sample Collection & Handling Guide for tube recommendation by sample type.

Chemistry sample collection & shipping

Comprehensive information on procedures for sample collection, detailed instructions on the packaging and shipping process, and additional details for blood and urine chemistry tests.

Sample Requirements - Icon

Sample Requirements

Separated serum is preferred for most assays.

EDTA plasma, LH plasma, urine, and CSF are possible for various assays.

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Collection Instructions

Single analyte ~40 μL, standard panels between 50-270 μL.

Dilution strategies are also available for lower volumes for some analytes.

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Sample Storage

Most specimens require storage at 2-8°C if shipping within 24 hours of collection though some analytes should be maintained frozen.

If stored longer than 24 hours, freeze samples in transport tubes.

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Shipping

Ship samples on cold packs or dry ice as required based on requested tests and sample age.

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Turnaround Time

Most standard assays are reported within 3 business days.

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Additional Information

Dilution strategies are possible. Please consult with your account manager.

Please refer to our Tube Sample Collection & Handling Guide for tube recommendation by sample type.

Coagulation sample collection & shipping

Please find comprehensive information regarding the procedures for sample collection, detailed instructions on the packaging and shipping process, and additional details for coagulation.

Sample Requirements - Icon

Sample Requirements

Citrated plasma is the preferred sample type for most coagulation panels. Sodium oxalate, EDTA, and heparin are not suitable and are not accepted.

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Collection Instructions

Fill tube to appropriate volume; proper blood to anticoagulant ratio is important for accurate results. Rapid separation of citrated plasma from whole blood is recommended.

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Sample Storage

Freeze separated plasma immediately at -20°C.

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Shipping

Shipping on dry ice is recommended. Samples should remain frozen until analysis.

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Turnaround Time

Most standard assays are reported within business 3 days.

 

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Additional Information

Coagulation testing is performed at the North Grafton, MA laboratory.

Please refer to our Tube Sample Collection & Handling Guide for tube recommendation by sample type.

Inflammatory markers sample collection & shipping

Please find comprehensive information regarding the procedures for sample collection, detailed instructions on the packaging and shipping process, and additional details for inflammatory markers.

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Sample Requirements

Cytokines: serum, plasma, cell culture supernatant, or standardized tissue homogenates.

CRP or Haptoglobin: serum

Fibrinogen: citrate or EDTA plasma

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Collection Instructions

Cytokines: 35 µL

CRP and Haptoglobin: varies by species

Fibrinogen: 160 µL or 1mL EDTA

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Sample Storage

Freeze separated plasma immediately at -20°C.

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Shipping

Ship sample on cold packs or dry ice. 

Samples for cytokine analysis must be shipped on dry ice to our lab in Columbia, MO only

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Turnaround Time

10 business days

 

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Additional Information

Cytokines must remain frozen in transit.

Thawed samples cannot be tested.

Bone Marrow cytology sample collection & shipping

Please find comprehensive information regarding the procedures for sample collection, detailed instructions on the packaging and shipping process, and additional details for bone marrow collection.

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Sample Requirements

Varies based on service. Client Support or your account manager can provide more details as needed.

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Collection Instructions

Varies based on service. Please contact Client Services or your account manager for more details.

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Sample Storage

Smears should be held at room temperature.

Do not refrigerate.

Do not stain or coverslip

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Shipping

Ship slides in cardboard or plastic containers to prevent breaking.

Ship at room temperature - ship separately from cold or frozen samples.

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Turnaround Time

Varies based on services requested.

 

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Additional Information

Proper collection techniques are vital for obtaining optimal results.

Consultations can be arranged.

Histology sample collection & shipping

Please find comprehensive information regarding the procedures for sample collection, detailed instructions on the packaging and shipping process, and additional details for histology.

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Sample Requirements

Organs

Tissue (for Histology)

Organoids

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Collection Instructions

Place tissues in formalin for at least 24 hours before shipment. Tissue to formalin ratio should be 1 to 20 for proper fixation.

Whole rodent and tissues such as lung, brain, bone marrow and spinal cord have specialized collection protocols.

Make sure tissues are not tightly packed in jars or cassettes. Smaller tissues can be placed in a cassette or submitted attached to surrounding organs.

Label cassettes with a pencil. Even indelible ink will fade during processing.

Tissues can be shipped in 70% alcohol or formalin. If you plan to perform IHC testing after preparation, please consult with our Client Support Services team for the proper fixation protocol.

For organoids, place in formalin for 1 hour and transfer to 70% EtOH for shipment.

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Sample Storage

Store fixed samples at room temperature. Frozen samples must be stored and shipped on dry ice.

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Shipping

To preserve sample integrity and prevent leakage samples should be triple-bagged with each layer tied, knotted or secured individually.

Screw-topped containers are preferred. Make sure the lid is tightly secured to the jar and place a layer of all-purpose sealing film or tape to secure the lid to the jar.

Invert the jar to check for leaks and reseal if needed.

Place jar(s) into one gallon sealable bag with absorbent material such as paper towels and seal the bag.

Place samples in a sealable bag in a second sealable bag and seal or double-line (one bag inside of another) the shipping box with large garbage bags and tie off each bag separately.

Prior to knotting the first garbage bag, place absorbent packing materials around the bagged samples to not only absorb any leaked fluid but to prevent jostling and stabilize samples during shipment.

If sample jars are too large to seal in a one gallon sealable bag, you can also use garbage bags to triple line the shipping container.

Absorbent material should be placed around the samples in the first garbage bag prior to tying a knot in the bag.

Place the Histology Submission Form(s) or online submission packing slip and other supporting documents (if needed) on the outside of the second garbage bag.

Do not tape the inventory form to the outside of the box or place with samples in the same sealable bag.

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Turnaround Time

Varies based on services requested.

 

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Additional Information

Proper collection techniques are vital for obtaining optimal results. Consultations can be arranged.